$260,000 Given to Major Initiatives

The Research Centre on Aging Supports Four Major Initiatives to Increase Research Value

  • Alzheimer: working with GMF
    • Working with the GMF de l'Estrie to Combat Alzheimer's Disease
      What?
      A volunteer recruitment platform for participants with memory problems.
      Why?
      Only 5% of patients followed by the memory clinic of the CIUSSS de l’Estrie – CHUS (Sherbrooke) participate in research projects. The objective is to double this number.
      How?
      • A research nurse will build ties between the memory clinic and family medicine groups (GMFs) in Estrie.
      • Optimization of the web platform recherche-cerveau-sherbrooke.ca to facilitate the recruitment of persons seeking information on the disease.
      Chercheurs
      Researchers: Stephen Cunnane and Tamàs Fülöp, With Guy Lacombe, Christian Bocti, Daniel Tessier, and Dominique Lorrain (lead investigators), accompanied by Hélène Pigot and Rona Graham (collaborating investigators).

  • Seniors: living lab
    • A Living Research Laboratory with Seniors
      What?
      In the short term, the creation of a "living lab"/Age-friendly communities within which research, experimentation, and implementation with communities will interact mutually.
      Why? 
      To lower the physical and social barriers to the participation of seniors in activities of daily living, both at home and in the community.
      How?
      • A participative research approach with seniors focusing on 4 priorities: living, transportation, communication and respect/social inclusion.
      • Creation of a natural laboratory which recreates familiar and controlled environments (e.g., driving simulator, ATM) or makes it possible to experiment with new technological aides (e.g., stair lift).
      • Reorganization of existing elements in the environment to foster the development of "Age-Friendly" environments.
      Researchers
      Véronique Provencher and Suzanne Garon, with Mélanie Levasseur, Marie Beaulieu, and Manon Guay – Collaborators: Dany Baillargeon and Isabelle Lacroix (UdeS)

  • Aging Metabolism: join forces
    • Platform to study cellular and physiological mechanisms to gain a better understanding of aging metabolism
      What?
      A global research platform to study aging metabolism. 
      Why?
      To gain a better understanding of why aging metabolism leads to metabolic disorders which in turn may lead to type-2 diabetes or Alzheimer's disease.
      How?
      • Procurement of new equipment
      • Intensification of collaborations among researchers and with the tissue bank of the CHUS
      • Becoming the Québec centre responsible for collecting data for the Canada-wide E-ParaDiGM (Exercise - Physical Activity – Diabetes Glucose Monitoring) study.
      Researchers
      Eléonor Riesco, with Isabelle Dionne, Daniel Tessier, Mélanie Plourde, and Martin Brochu – Collaborators: Marie-France Langlois (UdeS) and Normand Boulé (University of Alberta)

  • 3D Brain
    • A 3D Model of the Brain 
      What?
      Construction of a three-dimensional (3D) "mini-brain" to study the behaviour of neuron cells responding to conditions leading to Alzheimer's disease.
      Why?
      Considering recent experimental data, we assume that amyloid beta (Aβ) is not not the direct causal factor of Alzheimer's disease. The question is: what is the agent which accelerates the process?
      How?
      • Transform the existing 3D platform by adapting it to microglia-neuron and astrocyte-neuron single cultures and co-cultures in order to expose them to a variety of stress factors (infections, oxidative stress, etc.).
      Researchers
      Abdel Khalil with the researchers of the axis on the biological mechanisms of aging. – collaborator: Stephen Cunnane


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